منابع مشابه
Functions of the intermediate filament cytoskeleton in the eye lens.
Intermediate filaments (IFs) are a key component of the cytoskeleton in virtually all vertebrate cells, including those of the lens of the eye. IFs help integrate individual cells into their respective tissues. This Review focuses on the lens-specific IF proteins beaded filament structural proteins 1 and 2 (BFSP1 and BFSP2) and their role in lens physiology and disease. Evidence generated in st...
متن کاملCalcium-induced degradation of the lens cytoskeleton.
We would like to thank Dr Jenny Bruce, Dr Virginia Lee, Dr Bill Schlaepfer and Dr Paul Shneidman of the University of Pennsylvania for contributing materials for these studies. J.A.B.N. holds an M.R.C. research studentship and M.J.C. is supported by grants from S.E.R.C. (GR/F5 1 197) and N.I.H. (NS274 18). 1. Shneidman, P. S., Carden, M. J., Lees, J. F. & Lazzarini, R. A. (1 988) Mol. Brain Res...
متن کاملPrediction of Refractive Outcome of Second Eye with Partial Adjustment of Intraocular Lens Power of the First Eye
Background and Objective: This study aimed at comparing the results of refractive cataract surgery in patients undergoing sequential surgeries in both eyes. Considering the preoperative refraction and final refraction of the first eye, it is possible to correct the refrative result of cataract surgery using the adjustment of the second eye intraocular lens (IOL) power. Materials and Methods: T...
متن کاملDisulfide bond formation in the eye lens.
The disposition and disposal of the -SH groups of the lens during aging and cataractogenesis have been investigated by laser Raman spectroscopy as a noninvasive microprobe in the intact living lens. In this procedure -SH and -S-S- give unique discrete Raman signals (at 2580 and 508 cm-1) that may be used to calculate relative concentrations in a very small volume of the lens. We present evidenc...
متن کاملMolecular interactions in the eye lens.
Introduction The lens is a cellular structure formed from elongated fibre cells aligning into concentric layers that stack together with the organization of a uni-axial crystal 111. Within the fibre cells, where protein turnover is low, protein components are packed together [2-41 with short-range order [S]. The high protein concentration is important both for refraction and transparency. Globu...
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ژورنال
عنوان ژورنال: Eye
سال: 1999
ISSN: 0950-222X,1476-5454
DOI: 10.1038/eye.1999.115